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[135] investigated the effects of Que on pulmonary fibrosis in mice and found that it reversed the increased expression of collagen markers such as collagen, type I, alpha 2 and fibronectin 1 associated with the extracellular matrix in bleomycin-induced mice

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With respect to liver metabolism, studies have shown that Scrophulariae Radix significantly regulates phospholipid metabolites such as phosphatidylcholine and phosphatidylethanolamine, aiding in restoring lipid metabolism balance and preventing common lipid metabolic disorders in hyperthyroid patients (102)

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