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Specifically, if microclots themselves lead to AF (as do other particulates, see above), one mechanism is their known membrane activities that would more or less directly cause channelopathies, which are themselves known to be causative in AF, especially when inherited [403,404,405,406,407]

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This tolerance partly explains the alertness of chronic alcohol users at blood alcohol levels that, in others, would cause coma or death [238,239,240,241]