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Initial reports that a gain-of-function polymorphism (L503F variant, rs1050152) in SLC22A4 that increased transport efficiency of ergothioneine was associated with increased risk of Crohnβs disease (56) were subsequently shown to have been confounded by the SLC22A4 gene being in linkage disequilibrium with the interferon regulatory factor 1 ( IRF1 ) gene, which was the locus conferring Crohnβs disease susceptibility (57)
cat:immunity
Size:50 MG
Testosterone acts on androgen receptors throughout the kidney
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