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The FDA ultimately decides whether to add a substance to the list
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Secondary endpoints included the proportion of participants achieving ≥5% and ≥10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and β-cell function
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