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A current area of scientific focus involves testing combinations of synthetic peptides to see if they produce a synergistic effect
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The findings that loss of claudin-7 expression induces sloughing of intestinal epithelial cells (claudin-7 KO mice), possibly by disrupting the complex between claudin-1, claudin-7 and β1-integrin, highlights the previously underappreciated roles of TJ proteins in cell–matrix interactions
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