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Notably, a study using a combined transcriptomic, proteomic, metabolomic approach in addition to hierarchial clustering on human prefrontal cortex tissue in order to detect molecular signatures associated with schizophrenia found alterations in proteins associated with mitochondrial function and oxidative stress responses (Prabakaran et al
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and stimulate phosphofructokinase-1 (PFK-1), a key glycolytic enzyme [35-37]
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