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In a flask were placed 2-[(4S)-4-amino-2-hydroxy-pentyl]-6-bromo-7-fluoro- isoquinolin-l-one (7.09 g, 20.7 mmol), 5-chloro-4-(trifluoromethyl)-2-(2- trimethylsilylethoxymethyl)pyridazin-3-one (8.15 g, 24.8 mmol), triethylamine (14.4 mL, 103 mmol), and DMF (40 mL)

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Int J Drug Dev Res 3 38.Narang N, Sharma J (2011) Sublingual mucosa as a route for systemic drug delivery

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