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Tregs actively absorb lactic acid via monocarboxylate transporter 1 (MCT1) in low-glucose environments, which promotes NFAT1 translocation into the nucleus, thereby increasing liver tumors PD-1 expression [50]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Montine TJ, Neely MD, Quinn JF, Beal MF, Markesbery WR, Roberts LJ, Morrow JD
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