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Interestingly, it can take years for B12 stores to deplete to a point where a deficiency becomes apparent: Vitamin B12 deficiency affects multiple systems, and sequelae vary in severity from mild fatigue to severe neurologic impairment
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This established connection between NNMT overexpression and adipose metabolic dysfunction is the biological foundation for 5-Amino-1MQ’s research relevance in obesity biology
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