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In endometrial cancer, similar results were observed, with high IDO expression in tumor cells correlating with greater tumor cell invasion and increased lymph node metastasis and reducing both overall survival and disease-free progression (Figure 3B and Table 1) [78]
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Experimental work confirms these predictions, demonstrating increased BDNF and phosphorylated CREB expression in hippocampal neurons (Feng et al., 2025)
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