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Introduction The main function of the adipocyte is to act as a buffer for the storage of excess fatty acids (FAs) as inert triacylglycerols (TAGs) in organelles termed lipid droplets (LDs) (1)

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Key priorities include validating microbiome-based risk biomarkers, conducting multicenter RCTs in high-altitude cohorts, and establishing region-specific safety guidelines to ensure equitable and safe translation