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What happened when AOD-9604 reached human trials AOD-9604 was developed commercially by Metabolic Pharmaceuticals (Australia), building on the original Ng laboratory work, and it went further in clinical development than HGH Fragment 176-191 ever did: roughly six randomized, placebo-controlled human trials, about 900 subjects total, run in Australia and the UK between roughly 2001 and 2007

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But an enzyme active across that many tissues is not a narrow fat loss switch, and no study has followed healthy adults inhibiting it daily