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Effects of apoptosis-related proteins caspase-3, Bax and Bcl-2 on cerebral ischemia rats
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Key Takeaways The TIPO-1 phase II RCT (n=203) showed 10.6% body weight loss at 24 weeks with 1.0 mg oral daily versus 2.2% with placebo, making tesofensine one of the strongest weight-loss signal compounds in phase II history
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