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For instance, a better evaluation of the mechanisms of regulation, gene expression of involved enzymes in specific tissues during the lifespan, the formation and use of SO 4 2- /H 2 S within cells is prospected together the investigation of S organic species which interact with metals/semi-metal in Fe-S clusters or Se-S species and their regulation, or the assessment of epigenetic DNA/protein SAM-dependent methylation patterns and the activity of the GSH/ GSSG system.
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