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Moreover, PUFA biosynthesis is itself a means of regulating sensitivity to ferroptosis: energy stress drives resistance to ferroptosis through activation of AMPK and its effects on limiting PUFA biosynthesis through control of acetyl-coenzyme A carboxylase (ACC) (Lee et al., 2020a) (Figure 2)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Arnhold J., Flemmig J
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