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Similarly, in blood cells, GPx activity (r = −0.279, p = 0.03) correlates negatively, and GR activity (r = −0.272, p = 0.065) tends to correlate negatively with ImmunolAge, whereas GSSG concentration (r = 0.423, p = 0.009) and GSSG/GSH ratio (r = 0.452, p = 0.000) correlate positively with ImmunolAge (Figure 4)

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subsequent subgroup analyses also revealed significantly higher plasma α-Syn levels in PD patients with walking difficulties and postural abnormalities than those with tremor (Malek et al