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For this review, we will explore the multifaceted role of SFN including evidence that supports SFN’s neuroprotective effects, its potential as an anticancer agent, and its ability to act as a chemoprotective agent

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In some assays, FRCs or dendritic cells were pre-treated with vCD44BP–Fc (20 μg ml −1 vCD44BP–Fc for 40 min at 4 °C) and washed to remove unbound vCD44BP–Fc prior to co-culture