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Ferroptosis in NAFLD Numerous studies have demonstrated the presence of iron overload in the liver tissue of NAFLD patients, that excess free iron can generate hydroxyl radicals and ROS via the Fenton reaction, promoting lipid peroxidation, and that redox imbalance is a central pathogenic mechanism of NAFLD and its progression [118, 126]
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For example, she says, it’s more common for people age 50-plus to take metformin, which is widely prescribed to lower blood sugar levels and manage type 2 diabetes
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