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doi: 10.1056/NEJM198812293192602 145 GoldDBowdenRSixbeyJRiggsRKatonWJAshleyRet al
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For example, iron ions cannot only act on the gastrointestinal mucosa, causing gastrointestinal damage, but also severely damage hepatocytes, causing lipid peroxidation, cell swelling, and tissue necrosis, leading to liver fibrosis or liver cancer ( The most direct effect of iron overload on cell damage is caused by lipid peroxidation can triggered by free iron ions
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