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Overall, macrophage polarization is more appropriately understood as the result of metabolic network remodeling, in which glucose metabolism, lipid metabolism, and amino acid metabolism do not operate in isolation, but instead form a highly coupled regulatory system at the levels of metabolic flux direction, signal transduction, and epigenetic regulation

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Having demonstrated that ABHD11 regulated Lp glu , we examined the effects of glutarate excess on glutaryl modifications