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In a study done in 2020 of children and teens, 89 participants had depression while 43 did not, and those who did have it showed lower B12 levels and higher homocysteine (a sulfur-containing amino acid)

EPA:Compliant

Size:3mL

Of course, the agents in these trials are not being developed for the US population alone, but the US is, and is likely to remain, the single biggest commercial opportunity for AOMs, with recent regulatory draft guidance proposing that trial demographics should reflect the US obese population