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First-line NHS approaches typically include: Structured dietary advice and calorie reduction Increased physical activity tailored to the individual Behavioural support through NHS weight management programmes or Tier 2/3 services Pharmacological treatment may be considered when lifestyle interventions alone are insufficient
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OCTN2, encoded by SLC22A5, is a sodium-dependent high-affinity carnitine transporter involved in active cellular carnitine uptake
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